Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) com

The Alberta clinical practice guidelines program is supporting appropriate, effective and quality medical care in Alberta through promotion, development and imp

The opioid overdose epidemic combined with the need to reduce the burden of acute pain poses a public health challenge. To address how evidence-based clinical p

There is currently heightened interest in optimizing health care through the generation of new knowledge on the effectiveness of health care services. The Unite

Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of