P148 Simultaneous Liver-Kidney Transplantation: A Single Centre Experience

Download or read book P148 Simultaneous Liver-Kidney Transplantation: A Single Centre Experience written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: IntroductionPost-liver transplant outcomes are significantly influenced by renal impairment. Simultaneous Liver Kidney transplantation (SLKT) was introduced as a means to decrease morbidity and mortality. There is published data from the United States regarding outcomes which is lacking for the UK population.We looked at 10-year liver and kidney outcome data from our large UK transplant centre and compared this to national data.MethodsA retrospective analysis was performed of SLKT recipients in our centre over 10 years (01/04/08-31/03/18) focusing on clinical outcomes compared to the national data from the UK Transplant Registry. Inclusion criteria were aged 17 or over at time of transplant; received both liver and kidney grafts and an elective procedure. Primary clinical outcomes included patient survival, graft survival, eGFR and complications. tResults19 patients were included (9 males and 10 females; median age 54 years) from our centre compared to 97 patients nationally in the period. SLKT indications were varied but similar across the groups (p 0.64). There is no difference in median time from listing to transplant in our centre compared to others (275 days (IQR 77-453) v 269 days (IQR 74-597)). Of patients receiving first grafts there was no difference in survival or graft status. The cause of death in three patients at our centre was infection. DiscussionSLK transplantation is a complex operation. Our centre has excellent outcomes comparable to national and published U.S. data.