Conditional Mutagenesis: An Approach to Disease Models

Download or read book Conditional Mutagenesis: An Approach to Disease Models written by Robert Feil and published by Springer Science & Business Media. This book was released on 2007-02-01 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse and their application to model human physiology and pathophysiology. The book illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. In addition, it considers the development of new drugs to treat human diseases.