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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442D: In Vitro Skin Sensitisation Assays addressing the Adverse Outcome Pathway Key Event on Keratinocyte activation
Language: en
Pages: 67

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442D: In Vitro Skin Sensitisation Assays addressing the Adverse Outcome Pathway Key Event on Keratinocyte activation

Authors: OECD
Categories:
Type: BOOK - Published: 2018-06-27 - Publisher: OECD Publishing

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This Test Guideline (TG) provides an in vitro procedure (the ARE-Nrf2 luciferase test method) used for supporting the discrimination between skin sensitisers an
Chemical Testing Using New Approach Methodologies (NAMs)
Language: en
Pages: 139

Chemical Testing Using New Approach Methodologies (NAMs)

Authors: Amy J. Clippinger
Categories: Science
Type: BOOK - Published: 2022-12-16 - Publisher: Frontiers Media SA

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins
Language: en
Pages: 63

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins

Authors: OECD
Categories:
Type: BOOK - Published: 2015-02-05 - Publisher: OECD Publishing

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This Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. It provides an in chemico procedure (D
OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation
Language: en
Pages: 53

OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation

Authors: OECD
Categories:
Type: BOOK - Published: 2023-07-04 - Publisher: OECD Publishing

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A Defined Approach (DA) consists of a selection of information sources (e.g in silico predictions, in chemico, in vitro data) used in a specific combination, an
Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans
Language: en
Pages: 263

Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans

Authors: Yanzhu Zhu
Categories: Science
Type: BOOK - Published: 2022-03-10 - Publisher: Frontiers Media SA

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