Scale-Up and Optimization in Preparative Chromatography

Scale-Up and Optimization in Preparative Chromatography
Author :
Publisher : CRC Press
Total Pages : 368
Release :
ISBN-10 : 0203909283
ISBN-13 : 9780203909287
Rating : 4/5 (287 Downloads)

Book Synopsis Scale-Up and Optimization in Preparative Chromatography by : Anurag Rathore

Download or read book Scale-Up and Optimization in Preparative Chromatography written by Anurag Rathore and published by CRC Press. This book was released on 2002-09-26 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; data comparisons from all stages of production; and industrial separation schemes for products such as synthetic molecules, antibody fragments, IgG, growth factors, and plasmid DNA. The book covers external constraints, separation economics, correlations for transport and kinetic phenomena, and the configuration and parameters of column design.


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