The marine derived natural product bryostatin 1 has been investigated in preclinical studies for a wide range of indications (cancer, Alzheimer's disease, HIV/A

Bryostatin 1 is a natural product that was originally isolated from the marine sponge Bugula neritina more than 50 years ago. Following its isolation, it has de

Protein kinase C (PKC) modulators are currently in clinical or preclinical development for a wide range of diseases that represent major causes of mortality and

The bryostatins are a family of structurally complex natural products isolated from the marine bryozoan Bugula neritina. Bryostatin 1 is currently being investi