The Fruit Fly, Drosophila Melanogaster: Modeling of Human Diseases (Part II)

Download or read book The Fruit Fly, Drosophila Melanogaster: Modeling of Human Diseases (Part II) written by Mariateresa Allocca and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The fruit fly, Drosophila melanogaster (Meigen, 1830) has been established as a key model organism thanks in part to their considerable biological similarity to mammals and an abundance of available genetic tools. Drosophila have been used to model many human disease states and have been critical in elucidating the genetic mechanisms contributing to them. Part I of this chapter covered basic Drosophila biology and relevant genetic tools available to Drosophila researchers. Here in part II, we review the use of Drosophila as a model organism to study neurodegenerative disorders, cardiovascular diseases, kidney diseases, cancer, metabolic disorders, and immune disorders, as well as key findings made in those fields thanks to Drosophila research.