Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders

Download or read book Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders written by Robert A. McArthur and published by Academic Press. This book was released on 2008-10-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Minimize the number of drug candidates that could later fail in human trials! These three volumes provide a unique examination of how animal models are evolving from "behavioral gut baths" to providing cross-species information relevant to human clinical responses. Each volume provides the views and experiences of leading pre-clinical and clinical investigators who are actively involved in translational research and experimental medicine. Each volume is devoted to specific disorders in three scientific fields: Psychiatric, Neurological, and Reward Deficit. - Clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process- Critical evaluation of animal and translational models improving transition from drug discovery and clinical development- Emphasis on what results mean to the overall drug discovery process- Exploration of issues in clinical trial design and conductance in each therapeutic area.