In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an internation

This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific ad

The present Key Event based Test Guideline (TG) addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. Skin sensi

Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU provides updated information on the EU Directive 2010/63/EU, which is the European Unio

This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in di