Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of m

This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in variou

This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design,

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps

"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development