Alzheimer's Disease From Molecular Mechanisms to Clinical Practices

Download or read book Alzheimer's Disease From Molecular Mechanisms to Clinical Practices written by Dildar Konukoğlu and published by Nobel Tıp Kitabevi. This book was released on with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Alzheimer’s Disease: From Molecular Mechanisms to Clinical Practices” explores the extensive perspective from the molecular foundations to the clinical diagnosis and treatment of Alzheimer’s disease. The book serves as a fundamental resource for understanding the neurobiological basis and molecular pathogenesis of Alzheimer’s, while also discussing the challenges and opportunities of transitioning from the laboratory to clinical settings. The initial sections of the book comprehensively examine the fundamental molecular characteristics of Alzheimer’s disease; these include the accumulation of amyloid-beta peptide, hyperphosphorylation of tau protein, and how these processes lead to synaptic dysfunction and neuronal death. These chapters provide strategies on how to understand the pathology of the disease at a molecular level and how this knowledge can be translated into clinical practice. Subsequent parts focus on the development and use of biomarkers for the early diagnosis of Alzheimer’s disease. In addition to the role of genetic predispositions, the effects of environmental factors and lifestyle choices on Alzheimer’s disease are discussed, highlighting the multifactorial nature of the disease. In conclusion, this book is a valuable resource for clinicians, researchers, and medical students specializing in the field. It provides essential scientific and practical information necessary for a better understanding and management of Alzheimer’s disease, offering a comprehensive perspective on the integration of molecular mechanisms with clinical applications.