Correlative Light and Electron Microscopy III

Download or read book Correlative Light and Electron Microscopy III written by and published by Academic Press. This book was released on 2017-06-01 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Correlative Light and Electron Microscopy III, Volume 140, a new volume in the Methods in Cell Biology, series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the third volume of Methods in Cell Biology covering current Correlative Light and Electron Microscopy (CLEM) methodologies. The field of CLEM is still growing and new combinations of imaging technologies provide exciting new insights. The chapters deal with different approaches to analyze the same specimen by more than one imaging technique to gain more and/or better information over applying each imaging technique separately. The strengths and application area of each presented CLEM approach are highlighted. This volume explores the aspects of sample preparation of diverse biological systemsfor different CLEM approaches and will serve as a valuable resource to researchers in the field of cell biology. Contains contributions from experts in the field Covered topics include targeted ultramicrotomy and high-precision correlation Presents recent advances and currently applied correlative approaches Gives detailed protocols allowing the application of workflows in one’s own laboratory setting Covers CLEM approaches in the context of specific applications Aims to stimulate the use of new combinations of imaging modalities