This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that

Oligonucleotides diffuse poorly through biological barriers, including cell membranes. They are also rapidly degraded in vivo by nucleuses. Aiming to improve th

Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell

Molecular biology is one of the most rapidly developing and at the same time most exciting disciplines. The key to molecular biology lies in the understanding o