Note on the Preparation of Mouse Tails for Intravenous Injection

Download or read book Note on the Preparation of Mouse Tails for Intravenous Injection written by Miriam Posner Finkel and published by . This book was released on 1951 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intravenous administration of solutions into mice is usually done by injection into one of the lateral tail veins. In albino mice these veins are quite conspicuous and easily entered, particularly if the mouse is a young adult, (2 to 3 months old). Customarily, a pre-injection dilatation of the vessels is accomplished by bathing the tail in warm water. The tail is then wiped dry, and the return of blood form the tail prevented by exerting gentle pressure at the base of the tail. As soon as the hypodermic needle has entered the swollen vein, the pressure is released and the injection completed.