This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals.

This document provides guidance for the testing of substances, and mixtures, classed as “difficult to test” for the purposes of determining their aquatic to

The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, whi

In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an internation

This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.