Tendons and Ligaments: Development, Pathogenesis, Tissue Engineering, and Regenerative Medicine

Download or read book Tendons and Ligaments: Development, Pathogenesis, Tissue Engineering, and Regenerative Medicine written by Dai Fei Elmer Ker and published by Frontiers Media SA. This book was released on 2024-09-27 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: In our rapidly aging society, tendon and ligament injuries pose a tremendous socioeconomic burden with a great impact on mobility and patient quality of life. Understanding tendon/ligament development and maturation, pathogenesis, wound healing, tissue engineering, and regenerative medicine approaches will be crucial. In this collection, we aim to showcase tendon and ligament research that spans the gamut of basic science to pre-clinical translation. These topics include but are not limited to tendon/ligament development and maturation, the pathogenesis of tendon and ligament injury, isolation and modification of stem cells and their products for regenerative medicine, identification and delivery of bioactive tenogenic/ligamentogenic molecules, development and characterization of bioactive and/or mechanically robust biomaterials in silico, in vitro, ex vivo, and in vivo for tissue engineering, as well as the use of novel multidisciplinary methodologies and technologies including systems biology and synthetic biology approaches for studying tendons and ligaments as well as enhancing their repair and regeneration. With this collection, we aim to expose readers to inter- and multi-disciplinary biological and bioengineering techniques and research, which will stimulate broader discussion and advance our understanding to improve tendon/ligament repair and regeneration.